AOD-9604 Dosing: 300mcg/Day Fat Loss Protocol (2026)

Affiliate disclosure: vendor links in this article are affiliate links — The Peptide Catalog may earn a commission if you buy through them, at no additional cost to you.

Where These Numbers Come From

AOD-9604 has a notable research history including animal studies, human clinical trials, and FDA GRAS evaluation.

Animal studies: Both hGH and AOD-9604 reduced body weight gain via increased fat oxidation and plasma glycerol levels without affecting IGF-1 or insulin (Ng et al., 2001). AOD-9604 stimulates lipolysis through beta-3 adrenergic receptor pathways (Heffernan et al., 2001). Oral doses of 500 mcg/kg reduced body weight gain in Zucker rats without affecting lean mass or blood glucose (Ng et al., 2000).

Human clinical context: AOD-9604 progressed through Phase 2 trials. Safety was confirmed with no significant adverse events. Efficacy was mixed -- weight loss observed in initial trials but not replicated in later studies that included intensive diet/exercise programs. No effects on IGF-1, insulin, or glucose were confirmed in humans.

Joint health: Intra-articular AOD-9604 enhanced cartilage regeneration in rabbit OA models, with combined AOD-9604 + hyaluronic acid outperforming either alone (Kwon & Park, 2015).

Stacking AOD-9604

GH + Fragment

AOD-9604 300 mcg AM + CJC-1295/Ipamorelin 100/100 mcg PM

GH secretagogue effects + targeted lipolysis

Fat Loss + Recovery

AOD-9604 300 mcg AM + BPC-157 500 mcg AM/PM

Body recomposition with joint/tissue support

Aggressive Fat Loss

AOD-9604 300 mcg AM + Tesofensine 0.5 mg oral

Peripheral lipolysis + central appetite suppression

Stacking tips: Community stacking protocols describe maintaining fasted morning timing for AOD-9604 and moving GH secretagogues to nighttime. Diet remains critical -- the lipolytic activity documented in animal trials targets fat loss but doesn't replace a caloric deficit.

Side Effects & Safety

GRAS status -- FDA Generally Recognized As Safe as a food ingredient

No GH axis effects -- does not alter IGF-1, insulin, or glucose levels

Injection site redness -- mild, standard for SC peptides

Mild headache -- infrequent

Slight stomach upset -- if injected too close to eating

Water retention -- rare, unlike full GH

No diabetogenic effects -- blood sugar neutral, no acromegaly risk

AOD-9604 has one of the cleanest safety profiles in the peptide space due to its GH fragment design. For more detail, see our AOD-9604 benefits guide.

mg to Units Conversion

On a standard 100-unit insulin syringe, each "unit" equals 0.01 mL (so 100 units = 1 mL). Once AOD-9604 is reconstituted, the conversion from a target dose to syringe units depends on the chosen dilution.

The two reconstitution ratios most often described in community protocols are below.

Reconstitution A: 5 mg vial + 2 mL BAC water (2.5 mg/mL) — the standard dilution from the Quick Reference above.

150 mcg

0.06 mL

6 units

300 mcg

0.12 mL

12 units

450 mcg

0.18 mL

18 units

600 mcg

0.24 mL

24 units

Reconstitution B: 5 mg vial + 3 mL BAC water (1.67 mg/mL) — more BAC water for larger, easier-to-measure draws.

0.09 mL

9 units

0.27 mL

27 units

0.36 mL

36 units

These conversions reflect the dilutions documented in community reconstitution protocols. They report how the math is described, not a recommended dosing schedule.

Core Supplies for This Protocol

The three essentials for running any reconstituted injectable: cold storage, accurate syringes, and metabolic tracking.

Cooluli Classic 4L Mini Fridge

Compact thermoelectric mini-fridge with heat/cool toggle. The most-mentioned dedicated peptide-storage fridge in research community sources — fits ~20 vials and runs quietly.

BD Ultra-Fine 31G 0.3cc 5/16" Insulin Syringes (Box of 90)

0.3cc 31G syringes — each gradation marks 1 unit (vs 2 units on 1cc), making sub-50-unit peptide doses accurate. BD Ultra-Fine is the most widely-cited brand in peptide community sources.

CONTOUR NEXT GEN Glucose Meter All-In-One Kit

Ascensia's CONTOUR NEXT GEN — the most clinically-validated home glucose meter. Includes 20 test strips + lancing device. Tracks the blood-sugar response GLP-1 users care about, especially during dose escalation.

As an Amazon Associate, The Peptide Catalog earns from qualifying purchases.