Dermorphine 8 peptide

Product Information

• Product Name

  Dermorphine 8 peptide

• Documents
• Sequence Shortening

  YaFWYPN-NH2

• Sequence

  H-Tyr-D-Ala-Phe-Trp-Tyr-Pro-Asn-NH2

• Length (aa)

  7

• Peptide Purity (HPLC)

  97.98%

• Molecular Formula

  C50H58N10O10

• Molecular Weight

  959.06

• Source

  Synthetic

• Form

  Powder

• Description

  Dermorphin and deltorphin are naturally occurring heptapeptides purified from skin extracts of the South American frog Phyllornedusa sauvagei that show high affinity and selectivity for μ and δ opioid receptors, respectively. They share a similar N-terminal tripeptide sequence Tyr-D-Xaa-Phe, where D-Xaa is either D-Ala (dermorphin) or D-Met (deltorphin), and have an amidated COOH terminus. The two dermorphin-like peptides(Dermorphin 1 and Dermorphin 8) have a similar affinity and selectivity for the mu opioid receptor as dermorphin.

• Storage Guidelines

  Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

• References
  • Mignogna G, Severini C, Simmaco M, et al. Identification and characterization of two dermorphins from skin extracts of the Amazonian frog Phyllomedusa bicolor. FEBS Lett. 1992;302(2):151-4.
• About TFA salt

  Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

  Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

  Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

  In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

• Molar Concentration Calculator

• Dilution Calculator

• Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.