Recovery article

HGH Fragment 176-191 2mg

HGH Fragment 176-191 2mg Research Handling Note: For best results in a research setting, allow both the peptide and chosen solvent to reach ambient laboratory temperature before reconstitution. This helps maintain structural integrity during dissolution. *Reco

By Recovery & Performance Peptides Editorial Team Published June 1, 2026

HGH Fragment 176-191 2mg

Research Handling Note:

For best results in a research setting, allow both the peptide and chosen solvent to reach ambient laboratory temperature before reconstitution. This helps maintain structural integrity during dissolution. *Reconstitution solutions are supplied separately.

Stock: 2588

Model: HGH Fragment 176-191 2mg

Molecular Formula: C78H123N23O22S2

SKU: HGH2-022

Research Only: Yes

Certificate of analysis

Description

Technical Data

HGH Fragment 176-191 2mg - High-Quality Research Peptide

HGH Fragment 176-191, offered at 2mg, is a high-quality specialised research peptide developed for advanced scientific exploration in metabolism and endocrinology. This product is ideal for laboratory settings where precision and reliability are paramount.

Product Name: HGH Fragment 176-191 2mg

Catalogue Number: HGHF176191-2mg

Molecular Formula: C78H125N23O23S2

Molecular Weight: 1817.1 g/mol

Purity: ≥98%

Form: Lyophilised Solid

Usage and Storage:

HGH Fragment 176-191 is supplied as a lyophilised solid to ensure maximum stability and ease of use in research environments. Due to the presence of highly hydrophobic amino acid sequences, this peptide may appear cloudy when reconstituted this is normal and does not affect its suitability for research use. For best results, we recommend reconstituting with acetic acid (AA) as noted in the product instructions. Please follow our website's detailed reconstitution and storage guidelines.

Synthesis and Quality Assurance:

HGH Fragment 176-191 is meticulously synthesised through a controlled process that guarantees high purity (≥98%) and stability, making it suitable for precise scientific studies. Our commitment to excellence ensures that each batch undergoes stringent quality control to meet the rigorous standards researchers require.

Legal and Safety Information:

UK-Peptides proudly provides HGH Fragment 176-191 strictly for scientific and research use. In alignment with our dedication to supporting the research community, we ensure our products meet stringent quality standards and legal requirements. Please note that our peptides, including HGH Fragment 176-191, are not designed for human consumption or clinical application.

If you require high-quality HGH Fragment 176-191 for your research in the UK, explore our range of peptides designed for scientific rigour and innovation.

Identification

Molecular Weight (g/mol)

1817.1 g/mol

Peptide Sequence

H-Tyr -Leu-Arg-lle-Va1-GIn-Cys-Arg-Ser-Va1-GIu-Gly-Ser-Cys-Gly-Phe-OH

Physical and Chemical Properties

Molecular Formula

C78H125N23O23S2

Physical Appearance

White lyophilised solid

Form

Sterile filtered white lyophilized (freeze-dried)

Solubility

Aqueous soluble

Appearance

White to off-white lyophilised powder

Melting Point

Not applicable (decomposes before melting)

Analytical and Quality Control

Mass Spectrum

Consistent with structure.

Purity %

>98%

Research Use and Safety

Caution

Research use only / Not for human or veterinary use

Intended Use

For laboratory research use only. Not for human or veterinary use.

Hazard Classification

Not classified as hazardous under GHS for research quantities

Storage, Handling and Stability

Storage Temperature, Opened

Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18°C. Upon reconstitution of the peptide it should be stored at 4°C between 2-21 days and for future use below -18°C.

Storage Temperature, Unopened

-20 °C recommended for long-term storage

Shelf Life

2 years unopened under recommended conditions

Reconstitution Stability

Stable for up to 28 days at 2-8 °C in aqueous solution under sterile conditions

CONNECTED / MODULES

Post-session references

Selected from shared article topics. Source links are retained where available.

COACH'S BOARD / KEY POINTS

HGH Fragment 176-191 and AOD-9604 are the same molecular structure. A 15-amino-acid sequence (positions 176–191) derived from the C-terminus of human growth hormone, with identical 1817 Da molecular weight and amino acid composition.
The AOD-9604 designation originated from clinical trials conducted by Metabolic Pharmaceuticals between 2004 and 2007, while Fragment 176-191 remains the standard biochemical nomenclature used in research supplier catalogs and academic publications.
Both compounds failed to achieve FDA approval for obesity treatment after Phase IIb trials showed insufficient weight loss efficacy (2.6% vs 1.8% placebo) despite acceptable safety profiles and no IGF-1 elevation.
The peptide retains lipolytic activity by activating beta-3 adrenergic receptors on adipocytes without binding to growth hormone receptors. Making it valuable for metabolic research isolating fat mobilization from anabolic growth signaling.
Lyophilized Fragment 176-191 maintains >95% purity for 21 days post-reconstitution when stored at 2–8°C in amber vials, but oxidation at cysteine residues accelerates degradation beyond 28 days or after freeze-thaw cycles.
Research labs should specify Fragment 176-191 or AOD-9604 based on protocol citation requirements rather than assuming functional differences. The molecular identity is identical across suppliers meeting GMP synthesis standards.

SOURCE / realpeptides.co ↗

Handling & safety lane

Source-derived education, not individual medical guidance or an instruction to dose.

DOSAGE SOURCE

HGH Fragment 176-191 Dosage Calculator

Get your personalized HGH Fragment 176-191 dosage for fat loss based on your body weight, experience level, and goals.

Evidence cooldown

Research context and source excerpts for a slower second read.

RESEARCH

Community Research

Join others researching HGH Fragment 176-191 — share findings, ask questions, and learn from real experiences HGH Fragment 176-191 is the fat-burning segment of human growth hormone, corresponding to amino acids 176 through 191 of the full GH molecule. It stimulates lipolysis and inhibits lipogenesis without the growth-promoting or insulin-disrupting effects associated with full-length HGH. AOD-9604 is a modified version of this fragment with an added N-terminal tyrosine residue. Mimics the lipolytic region of human growth hormone by stimulating fat breakdown through beta-3 adrenergic receptor pathways. Unlike full HGH, it does not bind the growth hormone receptor, so it does not increase IGF-1 levels or interfere with glucose metabolism. The fragment selectively targets adipose tissue to promote fat oxidation.

RESEARCH

Research and Development of HGH Fragment 176-191

The focus of research on HGH Fragment 176-191 lies in its targeted effects on fat reduction and metabolic processes without affecting human growth. Initially studied as part of broader research on human growth hormone, scientists identified that the amino acid sequence from 176 to 191 held specific fat-reducing properties. This led to the development of the isolated HGH fragment, which has since shown encouraging results in studies. Multiple studies, including those conducted in Saudi Arabia and other research institutions, have shown that HGH Fragment 176-191 can influence fat metabolism effectively. According to a Saudi research team, the peptide had a notable impact on reducing body fat in test subjects, with limited side effects compared to full HGH. [5] Scientific journals and publications have frequently referenced HGH Fragment 176-191. For example, studies published on PubMed highlight the potential of this fragment in managing obesity and reducing body fat percentage without impacting other body systems. Articles also discuss how HGH Fragment 176-191 affects enzymes involved in fat breakdown. [1] [4]

Product & matchup locker

Linked catalog and comparison files.

Comparison

HGH Fragment 176-191 vs Full-Length Growth Hormone

HGH Fragment 176-191 vs Full-Length Growth Hormone Discover how HGH Fragment 176-191 compares to full-length HGH 191AA in fat metabolism, IGF-1 activity, and systemic effects. Cho…

View details →

Comparison

What This HGH Fragment 176-191 Comparison Page Includes

Live HGH Fragment 176-191 pricing — Current prices across all tracked vendors, normalized to price per milligram for a fair apples-to-apples comparison regardless of vial size. CO…

HGH Fragment 176-191 2mg

Research Handling Note:

Certificate of analysis

HGH Fragment 176-191 2mg - High-Quality Research Peptide

Usage and Storage:

Synthesis and Quality Assurance:

Legal and Safety Information:

HGH Fragment 176-191 vs Full-Length Growth Hormone

What This HGH Fragment 176-191 Comparison Page Includes

HGH Fragment 176-191: Unpacking This Research Peptide

HGH Fragment 176-191 vs Full-Length Growth Hormone

HGH Fragment 176-191, A New Method for Weight Loss