MOTS-C 20mg Dosage Protocol | PeptideDosages.com
MOTS-C (20 mg Vial) Dosage Protocol MOTS-C Dosage Chart MOTS-c is dosed at 200 mcg–1 mg administered daily via subcutaneous injection in educational protocols. A 20 mg vial reconstituted with bacteriostatic water yields about 6.67 mg/mL. Most protocols titrate
MOTS-C (20 mg Vial) Dosage Protocol
MOTS-C Dosage Chart
MOTS-c is dosed at 200 mcg–1 mg administered daily via subcutaneous injection in educational protocols. A 20 mg vial reconstituted with bacteriostatic water yields about 6.67 mg/mL. Most protocols titrate gradually over roughly 10 weeks. This information is for research and educational use only.
Reconstitute: Add 3.0 mL bacteriostatic water → ~6.67 mg/mL concentration.
Typical daily range: 200–1,000 mcg once daily (gradual titration over 10 weeks).
Easy measuring: At 6.67 mg/mL, 1 unit = 0.01 mL ≈ 66.7 mcg on a U‑100 insulin syringe.
Storage: Lyophilized: freeze at −20 °C (−4 °F) or below; after reconstitution, refrigerate at 2–8 °C (35.6–46.4 °F) and use within 7 days for best potency.
MOTS-c is a 16–amino-acid mitochondrial-derived peptide (MDP) that acts as a metabolic regulator, primarily through AMPK activation[1][2]. Preclinical studies show it enhances insulin sensitivity, promotes fat oxidation, improves exercise capacity, and counters age-related metabolic decline[1][4]. No clinical trials have been completed in humans to date[8]. This educational protocol presents a once-daily subcutaneous approach with gradual titration.
Research context: For evidence on mechanisms, human and preclinical research, limitations, and safety, read MOTS-c Peptide: Benefits, Uses, Side Effects, Dosage, and Research.
Standard / Gradual Approach (3 mL = ~6.67 mg/mL)
Weeks 1–2
200 mcg (0.2 mg)
3 units (0.03 mL)
Weeks 3–4
400 mcg (0.4 mg)
6 units (0.06 mL)
Weeks 5–6
600 mcg (0.6 mg)
9 units (0.09 mL)
Weeks 7–8
800 mcg (0.8 mg)
12 units (0.12 mL)
Weeks 9–10+
1,000 mcg (1.0 mg)
15 units (0.15 mL)
Frequency: Inject once daily subcutaneously[7]. Stay at each dose level for approximately 2 weeks before increasing, and monitor for any adverse reactions[7].
For ≤10‑unit (≤0.10 mL) administrations, consider 30‑ or 50‑unit insulin syringes for improved readability.
Reconstitution Steps
Draw 3.0 mL bacteriostatic water with a sterile syringe.
Inject slowly down the vial wall; avoid foaming.
Gently swirl/roll until dissolved (do not shake vigorously).
Label with reconstitution date and refrigerate at 2–8 °C (35.6–46.4 °F), protected from light.
Use within 7 days for optimal potency[7].
Supplies Needed
Plan based on an 8–16 week daily protocol with gradual titration.
Peptide Vials (MOTS-C, 20 mg each):
8 weeks ≈ 2 vials
12 weeks ≈ 3 vials
16 weeks ≈ 5 vials
Insulin Syringes (U‑100):
Per week: 7 syringes (1/day)
8 weeks: 56 syringes
12 weeks: 84 syringes
16 weeks: 112 syringes
Bacteriostatic Water (10 mL bottles): Use ~3.0 mL per vial for reconstitution.
8 weeks (2 vials): 6 mL → 1 × 10 mL bottle
12 weeks (3 vials): 9 mL → 1 × 10 mL bottle
16 weeks (5 vials): 15 mL → 2 × 10 mL bottles
Alcohol Swabs: One for the vial stopper + one for the injection site each day.
Per week: 14 swabs (2/day)
8 weeks: 112 swabs → recommend 2 × 100‑count boxes
12 weeks: 168 swabs → recommend 2 × 100‑count boxes
16 weeks: 224 swabs → recommend 3 × 100‑count boxes