MOTS-c Dosage Calculator

Calculate the correct MOTS-c dose with the Perfect B Aesthetic Medicine interactive calculator: reconstitution, units, timing, and cycle for a supervised clinical protocol.

Perfect B Aesthetic Medicine | 06.24.26 | 4 min read.

This article is for educational purposes only and does not constitute medical advice. Peptide therapy requires evaluation and prescription by a licensed medical provider. Do not use this information to self-administer or self-diagnose. Contact Perfect B at (786) 502-2260 to schedule a clinical evaluation. This is one part of a larger plan, so see how peptide therapy is delivered under medical supervision at our Doral clinic as part of a complete, individualized plan. For more on this, see our guide to Semax Dosage Calculator, including what to expect and how it is handled at Perfect B in Doral.

How Do You Reconstitute MOTS-c?

MOTS-c is dispensed as 10 mg vials. Reconstitute each vial with a fixed volume of bacteriostatic water so the concentration lands where the protocol expects.

• Add 0.5 ml of bacteriostatic water to the 10 mg vial.
• This gives a concentration of 20 mg per ml, which works out to 0.2 mg per unit on a 1 ml insulin syringe.
• Each 10 mg vial covers 2 injections (5 mg each), so the 4 injection protocol uses 2 vials.
• Once reconstituted, store the vial refrigerated and use within the active 20 day protocol window.

What Is the Concentration of MOTS-c in Your Vial?

With the 10 mg vial reconstituted in 0.5 ml, the concentration is fixed, so your unit count maps directly to milligrams.

• 10 mg vial reconstituted with 0.5 ml BAC water = 20 mg per ml = 0.2 mg per unit.
• At 0.2 mg per unit, 25 units = 5 mg.
• One unit on a 1 ml (100-unit) insulin syringe equals 0.2 mg of MOTS-c.

How Many Units of MOTS-c Do You Inject Per Day?

Draw to the unit line on your insulin syringe, not to a milligram figure.

• Dose per injection: 25 units on a 1 ml insulin syringe (equal to 5 mg of MOTS-c).
• Total injections: 4 injections across the 20 day protocol, one every 5 days.
• Total mg per cycle: 4 injections x 5 mg = 20 mg of MOTS-c per cycle.
• Starting point: dose is fixed at 25 units from the first injection. No titration phase.

Draw 25 units on your 1 ml insulin syringe (5 mg per injection). One injection every 5 days for a total of 4 injections over the 20-day protocol. Fixed dose with no titration.

When Do You Inject MOTS-c?

Inject on the schedule the calculator returns above.

• Injection site: subcutaneous, abdomen.
• Timing: at night, at least 2 hours after your last meal.
• Frequency: one injection every 5 days, 4 injections total over 20 days.
• Site rotation: rotate the exact spot within the same abdominal area each session.

What Is the Cycle for MOTS-c?

MOTS-c is a cycled protocol, not a daily-for-life peptide.

• On phase: 20 day protocol (4 injections, one every 5 days).
• Off phase: 4 months pause.
• Repeat: patients typically run 2 full cycles per year on this protocol.
• Why the off phase matters: MOTS-c works on mitochondrial signaling. Continuous dosing past the 20 day window blunts that signal. The 4 month pause is not optional.

Clinical tip: days between injections are rest days. If you miss a day, apply when you can and count 5 days from there.

Want the Same Protocol Built Around Your Goals?

Perfect B Aesthetic Medicine’s peptide protocol tool is built on real clinical data from 2,000+ patients treated in Florida.

Answer 6 questions and see what patients with similar goals are running: which peptides they use, typical dosing, injection schedule, reconstitution steps, cycle length, and when they pause.

→ See patient protocols at peptides.perfectb.com

Why Calculate Your MOTS-c Dose at Perfect B Aesthetic Medicine and Not at Home

A calculator gives you the numbers. A clinic gives you the answer to whether those numbers are safe for you. The protocol behind the tool above runs the same way for every patient at Perfect B Aesthetic Medicine, and that is what separates a supervised cycle from a guess at the kitchen counter.

• Pharmacy-grade sourcing: your MOTS-c is dispensed through a licensed compounding pharmacy. Identity, purity, and sterility are documented. Grey-market online vials carry none of those guarantees.
• Pre-protocol screening: labs, medical history, and contraindications are reviewed before a single vial is prescribed. Active cancer, pregnancy, bleeding disorders, and uncontrolled diabetes change the answer.
• Measured response: you do not guess if MOTS-c is working. You measure response markers and any side effects across each cycle. The protocol can be adjusted when data justifies it.
• Reconstitution done right: a mistake at the BAC water step changes your dose by an order of magnitude. The clinic walks you through the first reconstitution so the math is correct from injection one.
• Real follow-up: the 20 day on, 4 months off cycle is monitored. If the protocol is not delivering, the clinic catches that early instead of two cycles later.
• Florida-based clinical context: Perfect B Aesthetic Medicine is the clinic with the most peptide patients seen in Florida. That volume means every parameter in the calculator has been pressure-tested across thousands of real cycles.

You can run the calculator at home. You should not run the protocol at home. The numbers are accurate, but they are only safe inside a clinical relationship that screens you, supervises you, and adjusts when your physiology calls for it.

Frequently Asked Questions

1. What is the correct MOTS-c dose for you?

25 units per injection on a 1 ml insulin syringe, equal to 5 mg per injection. One injection every 5 days for a total of 4 injections over 20 days.

2. How do you reconstitute your MOTS-c vial?

MOTS-c comes as 10 mg vials. Add 0.5 ml of bacteriostatic water per vial, which gives 0.2 mg per unit. Each vial covers 2 injections. Gently swirl. Refrigerate after reconstitution.

3. Where do you inject MOTS-c?

Subcutaneous, in the abdomen, at night. Rotate the exact spot within the same area each session.

4. Is this calculator a substitute for a consultation?

No. It surfaces the parameters the supervised protocol uses. The protocol itself starts with a medical evaluation, contraindication screening, and a written prescription from Perfect B Aesthetic Medicine.

• 📍 Visit us at Perfect B Aesthetic Medicine | 3905 NW 107th Ave, Suite 104, Doral FL 33178
• 📞 Call or message us at (786) 502-2260
• 💳 Buy Now Pay Later available: Cherry, Klarna, Afterpay, CareCredit

→ Book your peptide consultation at Perfect B Aesthetic Medicine today.