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Nootropic Peptides: Semax, Selank & More (2026)

3 peptides in this class Dihexa Target: HGF/c-Met agonist Angiotensin IV-derived research compound studied for synaptogenesis via the HGF/c-Met pathway. Preclinical and in-vitro only — no human trials, and the foundational mechanism papers were retracted in 20

3 peptides in this class

Dihexa

Target: HGF/c-Met agonist

Angiotensin IV-derived research compound studied for synaptogenesis via the HGF/c-Met pathway. Preclinical and in-vitro only — no human trials, and the foundational mechanism papers were retracted in 2025.

Selank

Target: GABAergic / tuftsin analog

Selank is a synthetic neuropeptide derived from tuftsin with anxiolytic and nootropic properties. Developed in Russia for anxiety and cognitive enhancement. Studied for mood regulation, memory, and immune modulation without sedative effects.

Semax

Target: BDNF expression / melanocortin modulation

Semax is a synthetic peptide derived from ACTH (4-10) with neuroprotective and cognitive-enhancing properties. Developed in Russia for stroke recovery and cognitive disorders. Studied for memory, focus, neuroplasticity, and BDNF stimulation.

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