Sermorelin 10mg Dosage Protocol | PeptideDosages.com

Sermorelin (10 mg Vial) Dosage Protocol

Sermorelin Dosage Chart

Sermorelin is dosed at 200 mcg–500 mcg daily via subcutaneous injection in educational protocols. A 10 mg vial reconstituted with bacteriostatic water yields about 3.33 mg/mL. This information is for research and educational use only.

Reconstitute: Add 3.0 mL bacteriostatic water → ~3.33 mg/mL concentration.

Typical daily range: 200–500 µg once daily at bedtime (gradual titration).

Easy measuring: At 3.33 mg/mL, 1 unit = 0.01 mL ≈ 33.3 µg on a U‑100 insulin syringe.

Storage: Lyophilized: refrigerate at 2–8 °C (36–46 °F); after reconstitution, refrigerate at 2–8 °C (36–46 °F) and use within 10–14 days[4].

Sermorelin is a synthetic growth hormone–releasing hormone (GHRH) analog that stimulates endogenous pituitary GH secretion[1]. Originally approved for pediatric growth hormone deficiency, it is studied for adult off‑label use to support physiologic GH output and IGF‑1 levels[2]. This educational protocol presents a once‑daily subcutaneous approach administered at bedtime to align with natural nocturnal GH release[3].

Research context: For evidence on mechanisms, human and preclinical research, limitations, and safety, read Sermorelin Peptide: Benefits, Uses, Side Effects, Dosage, and Research.

Standard / Gradual Approach (3 mL = ~3.33 mg/mL)

Weeks 1–2

200 µg (0.2 mg)

6 units (0.06 mL)

Weeks 3–4

300 µg (0.3 mg)

9 units (0.09 mL)

Weeks 5–6

400 µg (0.4 mg)

12 units (0.12 mL)

Weeks 7–8

500 µg (0.5 mg)

15 units (0.15 mL)

Frequency: Inject once daily subcutaneously at bedtime. Bedtime administration is strongly recommended because endogenous GH secretion peaks during sleep[3]. This schedule uses the largest practical dilution (3.0 mL) to keep per‑injection units measurable with standard insulin syringes.

For ≤10‑unit (≤0.10 mL) administrations, consider 30‑ or 50‑unit insulin syringes for improved readability.

Reconstitution Steps

Draw 3.0 mL bacteriostatic water with a sterile syringe.

Inject slowly down the vial wall; gently swirl to dissolve (do not shake vigorously)[2].

Label with reconstitution date and refrigerate at 2–8 °C (36–46 °F), protected from light[2][4].

Wipe vial stopper with alcohol before each use; use a new sterile needle and syringe for each injection[2].

Supplies Needed

Plan based on an 8–week daily protocol with gradual titration (56 injections total).

Peptide Vials (Sermorelin, 10 mg each):

8 weeks (total ~19.6 mg consumed): 2 vials (20 mg total)

12 weeks (similar daily range): 4 vials

Tip: Have 1 extra vial as backup in case of spillage or loss.

Insulin Syringes (U‑100):

Per week: 7 syringes (1/day)

8 weeks: 56 syringes (recommend 1 × 100‑count box)

12 weeks: 84 syringes (1 × 100‑count box)

Preferred: 0.3–0.5 mL size with 28G–31G needle, 5/16″ to 1/2″ length for subcutaneous use. Consider 30‑ or 50‑unit syringes for low‑dose weeks for improved precision.

Bacteriostatic Water (10 mL bottles): Use ~3.0 mL per vial for reconstitution.

8 weeks (2 vials): 6 mL → 1 × 10 mL bottle

12 weeks (4 vials): 12 mL → 2 × 10 mL bottles

Contains benzyl alcohol preservative; do not use if allergic.

Alcohol Swabs: One for the vial stopper + one for the injection site each day.

Per week: 14 swabs (2/day)

8 weeks: 112 swabs → recommend 2 × 100‑count boxes

12 weeks: 168 swabs → recommend 2 × 100‑count boxes