Tesamorelin 5mg Dosage Protocol | PeptideDosages.com

Tesamorelin (5 mg Vial) Dosage Protocol

Tesamorelin Dosage Chart

Tesamorelin is dosed at 1 mg–2 mg daily by subcutaneous injection in educational protocols, typically at night. A 5 mg vial reconstituted with bacteriostatic water yields about 2.0 mg/mL. This information is for research and educational use only.

Reconstitute: Add 2.5 mL bacteriostatic water per 5 mg vial → 2.0 mg/mL concentration.

Standard daily dose: 2 mg (2000 mcg) once daily subcutaneously (FDA-approved protocol).

Easy measuring: At 2.0 mg/mL, 1 unit = 0.01 mL = 20 mcg on a U-100 insulin syringe.

Storage: Lyophilized: refrigerate at 2–8 °C (35.6–46.4 °F); reconstituted: refrigerate and use within 7 days with bacteriostatic water.

Tesamorelin is a synthetic 44-amino-acid peptide analog of Growth Hormone-Releasing Hormone (GHRH)[1]. It stimulates endogenous growth hormone release and raises IGF-1 levels, leading to enhanced lipolysis and metabolic benefits[2]. Tesamorelin is FDA-approved for reducing visceral adipose tissue in HIV-associated lipodystrophy and is studied for metabolic disorders and aging research[3][4].

Research context: For evidence on mechanisms, human and preclinical research, limitations, and safety, read Tesamorelin Peptide: Benefits, Uses, Side Effects, Dosage, and Research.

Standard FDA-Approved Protocol (2.5 mL = 2.0 mg/mL)

Week 1

1 mg / 1000 mcg

50 units (0.50 mL)

Weeks 2–12+

2 mg / 2000 mcg

100 units (1.00 mL)

Frequency: Inject once daily subcutaneously, preferably in the evening to coincide with nocturnal GH release[5][6]. The 2 mg daily dose is the standard FDA-approved regimen for HIV lipodystrophy[7][8]. A one-week titration at 1 mg may improve tolerability before advancing to the full 2 mg dose.

Reconstitution Steps

Draw 2.5 mL bacteriostatic water with a sterile syringe.

Inject slowly down the vial wall; avoid foaming.

Gently swirl until dissolved (do not shake).

Label and refrigerate at 2–8 °C (35.6–46.4 °F), protected from light.

Use within 7 days when reconstituted with bacteriostatic water[1].

Supplies Needed

Plan based on an 8–16 week daily protocol at the standard 2 mg dose (after Week 1 titration).

Peptide Vials (Tesamorelin, 5 mg each):

8 weeks ≈ 23 vials (112 mg total)

12 weeks ≈ 34 vials (168 mg total)

16 weeks ≈ 45 vials (224 mg total)

Insulin Syringes (U-100, 1 mL capacity):

Per week: 7 syringes (1/day)

8 weeks: 56 syringes

12 weeks: 84 syringes

16 weeks: 112 syringes

Bacteriostatic Water (10 mL bottles): Use 2.5 mL per vial for reconstitution.

8 weeks (23 vials): 57.5 mL → 6 × 10 mL bottles

12 weeks (34 vials): 85 mL → 9 × 10 mL bottles

16 weeks (45 vials): 112.5 mL → 12 × 10 mL bottles

Alcohol Swabs: One for the vial stopper + one for the injection site each day.

Per week: 14 swabs (2/day)

8 weeks: 112 swabs → recommend 2 × 100-count boxes

12 weeks: 168 swabs → recommend 2 × 100-count boxes

16 weeks: 224 swabs → recommend 3 × 100-count boxes