Source comparison
AOD-9604 vs HGH Fragment 176-191: Which Produces Better Before-and-After Results?
This is the most common comparison because both peptides share the same core sequence. AOD-9604 and HGH Fragment 176-191 both consist of amino acids 176-191 from human growth hormone. The only structural difference is AOD-9604's additional tyrosine residue at
This comparison does not assign a generated winner or score.
- This is the most common comparison because both peptides share the same core sequence. AOD-9604 and HGH Fragment 176-191 both consist of amino acids 176-191 from human growth hormone. The only structural difference is AOD-9604's additional tyrosine residue at the N-terminal end.
- Sequence
- hGH 176-191 + Tyr
- hGH 176-191
- Clinical trials
- Phase 2 (humans)
- None (humans)
- FDA GRAS
- Yes (2007)
- No
- Beta-3 lipolysis + anti-lipogenesis
- Half-life
- ~30 minutes
- Dosing
- 250-500 mcg/day
- Safety data
- Extensive
- Limited
- The tyrosine modification in AOD-9604 improves peptide stability and may slightly enhance lipolytic activity. Comparative studies in obese mice showed that AOD-9604 produced slightly greater fat reduction than the unmodified fragment at equivalent doses. However, both peptides were effective, and the difference was not large.
- The practical advantage of AOD-9604 over HGH Fragment 176-191 is the safety data. AOD-9604 has human clinical trial data and FDA GRAS status. HGH Fragment 176-191 has no human trial data and relies entirely on animal studies and extrapolation from AOD-9604's human data.
- For before-and-after outcomes, users report similar results from both compounds. The mechanism is effectively identical. If choosing between them, AOD-9604 has the stronger evidence base and regulatory standing.
- For a detailed comparison of all fat-loss peptide options, see our best peptides for weight loss comprehensive guide.