Source comparison
ARA 290 Same as ARA-290: Peptide Comparison
Amino Acid Length 11 residues 165 residues 165 residues + modified glycosylation ARA 290 is a fragment, not a full protein Molecular Weight ~1.3 kDa ~30 kDa ~37 kDa ARA 290 is 25× smaller than EPO Receptor Target Innate repair receptor (βCR + EPOR heterodimer)
This comparison does not assign a generated winner or score.
- Amino Acid Length
- 11 residues
- 165 residues
- 165 residues + modified glycosylation
- ARA 290 is a fragment, not a full protein
- Molecular Weight
- ~1.3 kDa
- ~30 kDa
- ~37 kDa
- ARA 290 is 25× smaller than EPO
- Receptor Target
- Innate repair receptor (βCR + EPOR heterodimer)
- EPOR homodimer
- Only ARA 290 avoids erythropoietic activation
- Erythropoietic Activity
- None. No red blood cell production
- High. Primary function
- High. Extended half-life version
- ARA 290 eliminates hematocrit risk entirely
- Plasma Half-Life
- 30–60 minutes
- 6–8 hours
- 25 hours
- Shorter half-life limits systemic exposure
- Clinical Application
- Tissue protection, neuropathy, inflammation
- Anemia, chronic kidney disease
- Anemia in cancer, CKD
- ARA 290 targets repair, not hematopoiesis