Source comparison
At a Glance: MT-2 vs Melanotan I Side-by-Side
Amino acid length 13 amino acids 7 amino acids Conformation Linear Cyclic (lactam bridge) Molecular weight ~1647 Da ~1024 Da Primary receptor target MC1R (selective) MC1R, MC3R, MC4R, MC5R (pan-agonist) MC2R binding No Metabolic stability Moderate (linear) Hig
This comparison does not assign a generated winner or score.
- Amino acid length
- 13 amino acids
- 7 amino acids
- Conformation
- Linear
- Cyclic (lactam bridge)
- Molecular weight
- ~1647 Da
- ~1024 Da
- Primary receptor target
- MC1R (selective)
- MC1R, MC3R, MC4R, MC5R (pan-agonist)
- MC2R binding
- No
- Metabolic stability
- Moderate (linear)
- High (cyclic)
- Relative potency at MC1R
- High
- Higher
- Research areas
- Pigmentation biology, MC1R pharmacology
- MC1R, MC4R (CNS), receptor selectivity studies, SAR
- Key structural modifications
- Linear with NDP-MSH modifications
- Cyclic, D-Phe, Nle, N-Ac/C-amide termini