Source comparison
Best Ipamorelin for Anti-Aging: Secretagogue Comparison
Research teams evaluating growth hormone secretagogues for age-related decline studies need baseline data on selectivity, potency, and handling requirements. This table compares the five most-studied compounds across critical research parameters. Ipamorelin 85
This comparison does not assign a generated winner or score.
- Research teams evaluating growth hormone secretagogues for age-related decline studies need baseline data on selectivity, potency, and handling requirements. This table compares the five most-studied compounds across critical research parameters.
- Ipamorelin
- 85–90%
- None detected
- Minimal (chronic use viable)
- 28 days at >95% potency
- 200–300 mcg per administration
- Optimal for long-term studies requiring clean GH pathway isolation. No confounding stress hormones
- GHRP-6
- 100% (reference)
- Cortisol +40%, prolactin +25%
- Low
- 28 days
- 100–200 mcg per administration
- Highest potency but introduces appetite stimulation and cortisol variables
- Hexarelin
- 120–140%
- Prolactin +35–40%
- High (significant after 4–6 weeks)
- 21 days
- 100 mcg per administration
- Strongest acute response but desensitization limits chronic study designs
- MK-677 (oral mimetic)
- 70–80% (oral bioavailability)
- Variable (15–25% of subjects)
- N/A (oral formulation)
- 10–25 mg oral daily
- Convenient dosing but less selective. Prolactin response unpredictable
- GHRP-2
- 90–95%
- Cortisol +20–30%
- 100–300 mcg per administration
- Middle ground between selectivity and potency. Moderate cortisol response