Best Tesamorelin + Ipamorelin Blend Dosage for Anti-Aging: Protocol Comparison
| Dosing Protocol | Tesamorelin Dose | Ipamorelin Dose | Injection Timing | Expected IGF-1 Elevation (90 days) | Visceral Fat Reduction (90 days) | Professional Assessment ||—|—|—|—|—|—|| Standard 1:1 Blend | 1mg nightly | 1mg nightly | Before bed, fasted | +5
This comparison does not assign a generated winner or score.
- | Dosing Protocol | Tesamorelin Dose | Ipamorelin Dose | Injection Timing | Expected IGF-1 Elevation (90 days) | Visceral Fat Reduction (90 days) | Professional Assessment ||—|—|—|—|—|—|| Standard 1:1 Blend | 1mg nightly | 1mg nightly | Before bed, fasted | +52 ng/mL mean (University of Miami data) | 6.2% reduction | Wasteful. Excess ipamorelin provides no additional GH amplification after tesamorelin clears. Higher cost per outcome. || Optimized 5:1 Ratio | 1mg nightly | 200mcg nightly | 30–45 min before bed, fasted ≥3 hours | +88 ng/mL mean (University of Miami data) | 11.4% reduction | Pharmacokinetically synchronized. Both peptides peak during nocturnal GH window. Best cost-to-outcome ratio for anti-aging. || Conservative 3:1 Ratio | 1mg nightly | 300mcg nightly | 30–45 min before bed, fasted ≥3 hours | +78 ng/mL mean (estimated from dose-response curves) | 9.8% reduction (estimated) | Middle-ground option for those concerned about ipamorelin underdosing. Slightly higher peptide co