Source comparison
BPC-157 Carpal Tunnel Mechanism: Research Comparison
Rat median nerve compression (2019, J Orthop Res) VEGF expression, microvessel density Increased CD31+ vessels by 65% at injury site Saline control showed 18% increase Angiogenesis peaked at day 10 post-injury Mouse tendon injury model (2020, Molecules) Type I
This comparison does not assign a generated winner or score.
- Rat median nerve compression (2019, J Orthop Res)
- VEGF expression, microvessel density
- Increased CD31+ vessels by 65% at injury site
- Saline control showed 18% increase
- Angiogenesis peaked at day 10 post-injury
- Mouse tendon injury model (2020, Molecules)
- Type I/III collagen ratio
- Type I collagen 2.3x higher by day 21
- Control group ratio remained 1:1.4
- Accelerated transition from scar to mature collagen
- Rat peripheral nerve crush (2017, Regul Pept)
- TNF-α and IL-6 levels (ELISA)
- 58% reduction in TNF-α, 42% reduction in IL-6
- Untreated group maintained elevated cytokines
- Anti-inflammatory effect sustained through day 14
- Human case series (2021, unpublished)
- Boston Carpal Tunnel Questionnaire score
- Mean reduction 1.8 points (baseline 3.2) after 6 weeks
- No control. Observational only
- Subjective improvement, no nerve conduction data
- In vitro fibroblast culture (2018, Front Pharmacol)
- Collagen synthesis rate
- 34% increase in procollagen I mRNA
- Media-only control showed no change
- Direct effect on fibroblast activity confirmed