Source comparison
BPC-157 Carpal Tunnel Research: Evidence Comparison
Rat median nerve crush (Zagreb, 2023) 10 mcg/kg IP daily × 28 days 34% faster nerve conduction recovery vs control Measurable improvement by day 14, peak at day 28 VEGF upregulation, axonal regrowth on EM Animal model. Human translation unconfirmed Rat carpal
This comparison does not assign a generated winner or score.
- Rat median nerve crush (Zagreb, 2023)
- 10 mcg/kg IP daily × 28 days
- 34% faster nerve conduction recovery vs control
- Measurable improvement by day 14, peak at day 28
- VEGF upregulation, axonal regrowth on EM
- Animal model. Human translation unconfirmed
- Rat carpal tunnel compression (comparative, 2022)
- 5 mcg/kg peri-neural every 48h × 21 days
- 87% baseline motor function recovery
- Plateau at day 21
- Reduced demyelination, Schwann cell proliferation
- Localized injection showed better efficiency than systemic
- Sciatic nerve transection model (2021)
- 20 mcg/kg systemic daily × 30 days
- Functional gait recovery, reduced fibrotic scarring
- Partial recovery by day 10, full by day 30
- FGF-2 expression, collagen remodeling
- Severe injury model. Exceeds typical carpal tunnel pathology
- Delayed-treatment control (2023)
- 10 mcg/kg starting day 7 post-injury
- Only 68% functional recovery vs 87% immediate-treatment
- Recovery plateau by day 28
- Delayed VEGF response, incomplete remyelination
- Suggests early intervention is critical for maximal benefit