Source comparison
BPC-157 for Gym Injury Recovery Research: Comparison of Study Models
Achilles Tendon Rupture (Rats) Randomised controlled, 28-day protocol 10 µg/kg daily, subcutaneous 60% faster healing; tensile strength 87% vs 52% at day 21 Histological collagen density, biomechanical load testing Most robust preclinical evidence; mechanism w
This comparison does not assign a generated winner or score.
- Achilles Tendon Rupture (Rats)
- Randomised controlled, 28-day protocol
- 10 µg/kg daily, subcutaneous
- 60% faster healing; tensile strength 87% vs 52% at day 21
- Histological collagen density, biomechanical load testing
- Most robust preclinical evidence; mechanism well-characterised through VEGF pathway
- Muscle Contusion (Rats)
- Placebo-controlled, 14-day protocol
- 10 µg/kg twice daily, intramuscular
- 50% reduction in haematoma size at 72 hours
- MDA oxidative stress markers, tissue inflammation scoring
- Strong evidence for acute inflammation modulation; oxidative protection is dose-dependent
- Ligament Injury (Rabbits)
- Observational cohort, 21-day protocol
- 500 µg/kg daily, local injection
- 40% improvement in ligament strength vs untreated
- Biomechanical stress-strain curves
- Higher dose required for ligament vs tendon; local administration outperformed systemic
- Corticosteroid-Impaired Healing (Rats)
- Dexamethasone + BPC-157 vs Dex alone
- Restored healing to baseline despite ongoing steroid use
- Collagen deposition, fibroblast migration assays
- Demonstrates FAK-paxillin pathway interaction; clinically relevant for athletes using corticosteroids