Source comparison
BPC-157 for Hamstring Injury Research: Study Type Comparison
Preclinical (Rat Achilles) Surgical transection 10 mcg/kg daily IP Tensile strength at 28 days +47% ultimate load capacity Most controlled evidence. Direct tendon repair mechanism demonstrated Preclinical (Rat Gastrocnemius) Contusion injury 10–200 mcg/kg dail
This comparison does not assign a generated winner or score.
- Preclinical (Rat Achilles)
- Surgical transection
- 10 mcg/kg daily IP
- Tensile strength at 28 days
- +47% ultimate load capacity
- Most controlled evidence. Direct tendon repair mechanism demonstrated
- Preclinical (Rat Gastrocnemius)
- Contusion injury
- 10–200 mcg/kg daily IM
- Collagen fiber alignment
- 53% faster Type I collagen deposition
- Mechanically closest to hamstring strain. Shows dose plateau at 10 mcg/kg
- Human Off-Label (Case Series)
- Grade II hamstring strain
- 250–500 mcg daily subQ
- Return-to-play timeline
- Self-reported 30–40% faster RTP
- No controls, no blinding. Cannot isolate peptide effect from rehab protocol
- In Vitro (Tenocyte Culture)
- Hydrogen peroxide oxidative stress
- 1–10 mcg/mL culture medium
- Fibroblast migration rate
- +62% migration speed vs untreated
- Confirms receptor-level mechanism but lacks tissue-level complexity