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Source comparison

BPC-157 for Long COVID Research: Study Comparison

Zagreb University (2024) 37 patients, open-label observational 250mcg SubQ twice daily for 12 weeks 6-minute walk distance, MoCA cognitive score, serum IL-6 Mean improvement 92m walk distance, 3.2-point MoCA increase, 38% IL-6 reduction Small sample, no placeb

This comparison does not assign a generated winner or score.

  • Zagreb University (2024)
  • 37 patients, open-label observational
  • 250mcg SubQ twice daily for 12 weeks
  • 6-minute walk distance, MoCA cognitive score, serum IL-6
  • Mean improvement 92m walk distance, 3.2-point MoCA increase, 38% IL-6 reduction
  • Small sample, no placebo control—results suggest signal worth larger trial
  • Croatian Post-Viral Recovery Consortium (2025)
  • 18 patients, case series
  • 500mcg SubQ daily for 8 weeks
  • Chalder Fatigue Scale, autonomic function testing
  • 61% reported clinically significant fatigue reduction, improved HRV in 72%
  • Uncontrolled design, patient-reported outcomes subject to placebo effect
  • Belgrade Institute preclinical model (2023)
  • Animal model (rats), viral-induced lung injury
  • 10mcg/kg daily for 21 days
  • Histological lung damage score, BAL inflammatory cell count
  • 47% reduction in alveolar damage, 52% reduction in neutrophil infiltration
  • Animal model—human translation uncertain, dosing not directly comparable
  • Mount Sinai exploratory analysis (ongoing, 2026)
  • Phase I safety trial, 45 patients planned
  • 250–750mcg SubQ daily for 16 weeks (dose-escalation)
  • Safety profile, preliminary biomarker panel
  • Results pending—expected Q3 2026
  • First U.S.-based controlled trial, will establish safety data for larger Phase II
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