Source comparison
BPC-157 for MCL Injury Research: Comparison
Rat MCL transection (Zagreb, 2010) 10 µg/kg IP daily Saline vehicle 62% increase in ligament tensile strength at 14d 40% faster functional recovery Gold-standard model for MCL healing. Demonstrates dose-dependent mechanical improvement Rat MCL crush injury (20
This comparison does not assign a generated winner or score.
- Rat MCL transection (Zagreb, 2010)
- 10 µg/kg IP daily
- Saline vehicle
- 62% increase in ligament tensile strength at 14d
- 40% faster functional recovery
- Gold-standard model for MCL healing. Demonstrates dose-dependent mechanical improvement
- Rat MCL crush injury (2018)
- 10 µg/kg IP + drinking water
- Untreated control
- Improved collagen fiber alignment, reduced inflammatory markers
- Histological maturity achieved 10d earlier
- Dual-route administration showed additive benefit. Suggests systemic + local effects
- Rat Achilles tendon model (comparative)
- Saline + NO inhibitor group
- Counteracted L-NAME-induced healing impairment
- Normalized healing despite NO pathway blockade
- Cross-tissue validation. MCL findings extend to other tendon/ligament structures
- Gastrocnemius muscle injury (2017)
- Saline control
- Elevated VEGF/EGF expression, faster functional recovery
- Return to baseline strength 7d earlier
- Confirms growth factor modulation is conserved across soft tissue injury types