Source comparison
BPC-157 for Meniscus Tear Research: Comparison of Study Protocols
The following table compares key parameters across representative BPC-157 for meniscus tear research studies to illustrate variability in methodology and outcomes. J Cell Physiol (2019) Rat, full-thickness tear 10 µg/kg daily, IA 28 days Tensile strength recov
This comparison does not assign a generated winner or score.
- The following table compares key parameters across representative BPC-157 for meniscus tear research studies to illustrate variability in methodology and outcomes.
- J Cell Physiol (2019)
- Rat, full-thickness tear
- 10 µg/kg daily, IA
- 28 days
- Tensile strength recovery
- 58% vs 22% control
- +40% vs baseline
- Strong histological improvement; short timeline limits remodelling assessment
- Regul Pept (2021)
- Rabbit, scaffold-augmented repair
- 5 µg/kg daily, IA
- 56 days
- Tissue integration
- 2.4× control score
- +220% vs control
- Scaffold synergy notable; longer timeline shows sustained collagen deposition
- Eur J Pharmacol (2020)
- Rat, partial meniscectomy model
- 15 µg/kg daily, SC
- 42 days
- Cartilage degradation markers
- Not assessed
- Systemic route less effective than IA; limited meniscus-specific endpoints
- Biomed Pharmacother (2022)
- Rabbit, microfracture + peptide
- 10 µg/kg EOD, IA
- 84 days
- Glycosaminoglycan content
- 1.8× control score
- +160% vs control
- Longest timeline published; shows continued matrix synthesis past 8 weeks
- IA = intra-articular; SC = subcutaneous; EOD = every other day. Collagen organisation scored via Modified O'Driscoll histological scoring system. Vascular density quantified via CD31 immunostaining.