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BPC-157 for Post-Surgery Healing Research: Study Comparison

This table summarises key controlled studies on BPC-157 in surgical recovery models, comparing injury type, dosing, timeline, and primary outcomes. Sikiric et al. (2020) Achilles tendon transection (rat) 10 mcg/kg SC daily × 14 days Tensile strength at day 14

This comparison does not assign a generated winner or score.

  • This table summarises key controlled studies on BPC-157 in surgical recovery models, comparing injury type, dosing, timeline, and primary outcomes.
  • Sikiric et al. (2020)
  • Achilles tendon transection (rat)
  • 10 mcg/kg SC daily × 14 days
  • Tensile strength at day 14
  • 78% normal strength vs 41% control
  • Most robust tendon healing data available. Effect size clinically meaningful
  • Krivic et al. (2008)
  • Intestinal anastomosis (rat)
  • 10 mcg/kg IP daily × 7 days
  • Anastomotic bursting strength
  • 2.4× higher bursting pressure
  • Critical for GI surgery research. Adhesion reduction without compromising strength
  • Cerovecki et al. (2010)
  • Femoral fracture (rat)
  • Callus mineralisation (μCT)
  • 34% increase in bone volume/total volume
  • Moderate effect. Most relevant during early callus formation phase
  • Novinscak et al. (2008)
  • Quadriceps detachment (rat)
  • Muscle reattachment strength
  • 63% improvement in load-to-failure
  • Suggests utility in muscle-tendon junction injuries specifically
  • Tkalcevic et al. (2007)
  • Full-thickness skin wound (rat)
  • 1 mcg topical daily × 10 days
  • Epithelialisation rate
  • 60% faster wound closure
  • Topical administration effective. Relevant for open wound models
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