Source comparison
BPC-157 Ligament Repair: Clinical Evidence Comparison
Rat Achilles Tendon (Zagreb, 2010) Complete transection 10mcg/kg daily subcutaneous 14 days Complete ligament-bone reconnection vs 42 days control VEGF-mediated angiogenesis Rat MCL Tear (2013) Grade II partial tear 10mcg/kg twice daily 10 days 60% greater ten
This comparison does not assign a generated winner or score.
- Rat Achilles Tendon (Zagreb, 2010)
- Complete transection
- 10mcg/kg daily subcutaneous
- 14 days
- Complete ligament-bone reconnection vs 42 days control
- VEGF-mediated angiogenesis
- Rat MCL Tear (2013)
- Grade II partial tear
- 10mcg/kg twice daily
- 10 days
- 60% greater tensile strength
- Increased Type I collagen density
- Rat Rotator Cuff (2018)
- Supraspinatus detachment
- 500mcg total daily dose
- 21 days
- Histological continuity restored
- Fibroblast proliferation rate 2.1× baseline
- Human Case Series (off-label, 2022)
- Mixed tendon/ligament injuries
- 250–500mcg twice daily
- 4–6 weeks
- Self-reported pain reduction 70%
- Not mechanistically analyzed