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BPC-157 Nerve Repair Research: Comparison of Key Studies
The table below compares landmark studies evaluating whether BPC-157 help nerve repair research outcomes across different injury types and measurement endpoints. Sikiric et al. (2018). Rat sciatic crush Crush injury 10 mcg/kg IP daily Sciatic functional index
This comparison does not assign a generated winner or score.
- The table below compares landmark studies evaluating whether BPC-157 help nerve repair research outcomes across different injury types and measurement endpoints.
- Sikiric et al. (2018). Rat sciatic crush
- Crush injury
- 10 mcg/kg IP daily
- Sciatic functional index (SFI) at day 21
- 40% faster return to baseline SFI
- Strongest signal for functional recovery in crush model
- Krivic et al. (2021). Rat sciatic transection + autograft
- Transection with 10mm gap
- Axonal density in graft at 28 days
- 25% higher axon count per field
- Modest benefit when structural continuity disrupted
- Tkalcevic et al. (2019). Acrylamide neuropathy
- Neurotoxic distal axonopathy
- Intra-epidermal nerve fiber density (IENFD)
- 30% higher IENFD preservation
- Neuroprotective against toxic degeneration
- Drmic et al. (2020). Chronic sciatic compression
- Compression neuropathy
- Gastrocnemius muscle fiber diameter
- 20% reduced atrophy vs saline
- Limits secondary muscle denervation
- Huang et al. (2022). Sciatic crush + electrophysiology
- 10 mcg/kg SC daily
- Compound muscle action potential (CMAP) amplitude recovery
- 50% greater CMAP amplitude at day 21
- Best electrophysiological evidence for functional reinnervation