Source comparison
BPC-157 Research Evidence: Study Type Comparison
Rat Achilles Tendon Model (2020) 40 rats 30% faster healing vs control; VEGF upregulation confirmed 28 days Strongest evidence for tendon repair; mechanism well-characterized Muscle Crush Injury Study (2019) 36 rats 35% faster fiber restoration; reduced TNF-α
This comparison does not assign a generated winner or score.
- Rat Achilles Tendon Model (2020)
- 40 rats
- 30% faster healing vs control; VEGF upregulation confirmed
- 28 days
- Strongest evidence for tendon repair; mechanism well-characterized
- Muscle Crush Injury Study (2019)
- 36 rats
- 35% faster fiber restoration; reduced TNF-α and IL-6
- 14 days
- Demonstrates anti-inflammatory effect; dose-response observed
- Human Clinical Trial
- 0 subjects
- No published data
- N/A
- Critical gap. Efficacy and safety in humans unverified
- In Vitro Fibroblast Study (2018)
- Cell culture
- Increased collagen synthesis by 45%
- 72 hours
- Supports proposed mechanism but lacks in vivo validation
- Ligament Healing Model (2017)
- 24 rats
- Increased GH receptor density by 40%
- 21 days
- Suggests growth factor pathway modulation; needs replication