BPC-157 Research Models: Comparison
Gastric Ulcer Days to 50% closure + histological score 5–10 µg/kg Intraperitoneal 60–75% faster closure vs control Most consistent model. High reproducibility, strong effect size, clinically relevant endpoint Achilles Tendon Tensile strength (N/mm²) + collagen
This comparison does not assign a generated winner or score.
- Gastric Ulcer
- Days to 50% closure + histological score
- 5–10 µg/kg
- Intraperitoneal
- 60–75% faster closure vs control
- Most consistent model. High reproducibility, strong effect size, clinically relevant endpoint
- Achilles Tendon
- Tensile strength (N/mm²) + collagen density
- 10–20 µg/kg
- Intramuscular
- 40–50% strength recovery improvement
- Mechanically validated. Directly measures structural repair, not just closure
- Skeletal Muscle Crush Injury
- Cross-sectional area recovery + inflammatory markers
- 10 µg/kg
- 30–45% faster regeneration
- Moderate effect size. Muscle has high baseline regenerative capacity, peptide benefit is incremental
- Ligament Tear (MCL)
- Histological score + biomechanical load-to-failure
- Local injection
- 25–35% improvement in load tolerance
- Limited vascular supply reduces angiogenic benefit. Smallest effect size across tissue types
- Corneal Injury
- Re-epithelialization rate + transparency score
- 1–5 µg/kg (topical)
- Topical drops
- 50–65% faster closure
- High epithelial turnover amplifies peptide effect. Dose requirements lower due to direct application
- Oral Mucosa Wound
- Closure rate + inflammatory cell count
- Systemic injection
- 40–60% faster closure
- High baseline healing rate limits observable effect size. Still significant vs control