Source comparison
BPC-157 Studied Meniscus Injury: Model Comparison
Rat radial tear Surgical scalpel incision through medial meniscus 10 mcg/kg IP daily 47% faster histological healing, increased collagen type I deposition 28 days Most common model. Shows clear angiogenesis and structural repair Rabbit longitudinal tear Arthro
This comparison does not assign a generated winner or score.
- Rat radial tear
- Surgical scalpel incision through medial meniscus
- 10 mcg/kg IP daily
- 47% faster histological healing, increased collagen type I deposition
- 28 days
- Most common model. Shows clear angiogenesis and structural repair
- Rabbit longitudinal tear
- Arthroscopic punch biopsy creating 5mm defect
- 5 mcg intra-articular 3x/week
- 2.3-fold higher vascular density, 34% improved tensile strength at 21 days
- 42 days
- Larger joint model confirms dose-dependent biomechanical improvements
- Rat degenerative model
- Monosodium iodoacetate injection inducing meniscal breakdown
- Reduced IL-6 by 38%, preserved cartilage volume on microCT
- 35 days
- Tests peptide effect on chronic degeneration, not acute injury