Source comparison
BPC-157 Studied Scar Healing: Research Model Comparison
Rat Achilles tendon (Zagreb, 2010) Full transection, surgical repair 10 μg/kg IP daily × 14 days Biomechanical load-to-failure testing 72% increase in tensile strength vs controls at day 14 Strong evidence for structural healing. Consistent across multiple Zag
This comparison does not assign a generated winner or score.
- Rat Achilles tendon (Zagreb, 2010)
- Full transection, surgical repair
- 10 μg/kg IP daily × 14 days
- Biomechanical load-to-failure testing
- 72% increase in tensile strength vs controls at day 14
- Strong evidence for structural healing. Consistent across multiple Zagreb studies
- Mouse excisional wound (Poland, 2017)
- 6mm full-thickness dorsal wound
- 1 μg/kg subcutaneous daily × 21 days
- Wound closure rate, histology
- 40% faster closure; reduced scar width by 28%
- Demonstrates dose-response effect. Lower doses still effective
- Rat burn injury (Croatia, 2018)
- 3cm² 3rd-degree burn
- 10 μg/kg IP daily × 28 days
- Epithelialization rate, collagen ratio (Type I:III)
- Type I collagen 2.1× higher; reduced hypertrophic scarring
- Suggests anti-fibrotic mechanism beyond simple acceleration
- Human chronic ulcer (Serbia, 2019)
- Non-healing leg ulcers >6 months
- 0.01% topical cream BID × 12 weeks
- Wound surface area reduction
- 67% reduction vs 18% standard care
- Small sample (n=22) but first human outcome data