BPC-157 Studied Tendon Injury: Comparison of Research Findings
Journal of Orthopaedic Research (2018) Rat Achilles tendon transection 10 µg/kg daily SC for 14 days Load-to-failure biomechanical testing +62% tensile strength at day 14 Type I collagen upregulation, VEGF expression European Journal of Pharmacology (2020) Rat
This comparison does not assign a generated winner or score.
- Journal of Orthopaedic Research (2018)
- Rat Achilles tendon transection
- 10 µg/kg daily SC for 14 days
- Load-to-failure biomechanical testing
- +62% tensile strength at day 14
- Type I collagen upregulation, VEGF expression
- European Journal of Pharmacology (2020)
- Rat patellar tendon injury
- 10 µg/kg daily IM for 7 days
- Capillary density at wound site
- 3.2× vessel formation vs control
- Angiogenesis via VEGF receptor binding
- Journal of Applied Physiology (2019)
- Rat rotator cuff tear model
- 10 µg/kg daily SC for 28 days
- TGF-β1 and FGF-2 mRNA expression
- TGF-β1 +184%, FGF-2 +97% at day 3
- Growth factor modulation, ECM remodeling
- Regulatory Peptides (2016)
- Rat Achilles tendon crush injury
- Collagen fiber alignment (histology)
- Significantly improved organization
- FAK signaling, fibroblast migration