Source comparison
BPC-157 Studied Ulcerative Colitis Research: Model Comparison
TNBS Colitis Intrarectal ethanol + TNBS Transmural, mixed Th1/Th17 7–14 days 10 mcg/kg IP daily Moderate. More Crohn's-like but validates mucosal healing Acetic Acid Colitis Intrarectal 4% acetic acid Superficial mucosal ulceration 5–10 days 10 mcg/kg IP or or
This comparison does not assign a generated winner or score.
- TNBS Colitis
- Intrarectal ethanol + TNBS
- Transmural, mixed Th1/Th17
- 7–14 days
- 10 mcg/kg IP daily
- Moderate. More Crohn's-like but validates mucosal healing
- Acetic Acid Colitis
- Intrarectal 4% acetic acid
- Superficial mucosal ulceration
- 5–10 days
- 10 mcg/kg IP or oral
- High. Closest to UC mucosal injury pattern
- Cysteamine Model
- Oral cysteamine 300 mg/kg
- Duodenal ulcers, some colonic
- 10–14 days
- 10 ng/kg to 10 mcg/kg
- Low. Primarily upper GI model
- DSS (Dextran Sodium Sulfate)
- 3–5% DSS in drinking water
- Epithelial barrier disruption
- 7–21 days (chronic)
- Not extensively studied
- Moderate. Chronic relapsing model but lacks immune memory