Source comparison
BPC-157 TB-500 Post-Surgical Research: Study Design Comparison
Achilles tendon transection (rat) 10 mcg/kg daily SQ 7.5 mg/kg 2×/week IP Tensile strength at 14 days +81% vs saline University of Zagreb, 2014 Full-thickness dermal wound (mouse) 500 mcg/kg daily IP 5 mg/kg 2×/week SQ Wound closure rate 35% faster closure NYU
This comparison does not assign a generated winner or score.
- Achilles tendon transection (rat)
- 10 mcg/kg daily SQ
- 7.5 mg/kg 2×/week IP
- Tensile strength at 14 days
- +81% vs saline
- University of Zagreb, 2014
- Full-thickness dermal wound (mouse)
- 500 mcg/kg daily IP
- 5 mg/kg 2×/week SQ
- Wound closure rate
- 35% faster closure
- NYU Langone, 2016
- Ligament repair (rabbit)
- 200 mcg/kg daily SQ
- 10 mg/kg 2×/week IP
- Collagen density (histology)
- +64% type I collagen
- Seoul National, 2018
- Post-surgical adhesion model (rat)
- 10 mcg/kg daily IP
- Not administered
- Adhesion score (gross + micro)
- −72% adhesion formation
- University of Pecs, 2017
- Bone fracture healing (rat)
- 2 mg/kg 3×/week IP
- Callus formation (X-ray)
- +40% mineralisation at 21 days
- Ankara University, 2020
- SQ = subcutaneous; IP = intraperitoneal. Dosing protocols reflect the most common ranges across peer-reviewed rodent models. Human-equivalent doses would require allometric scaling (typically divide by 6.2 for rat-to-human conversion) and are not established for these peptides.