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BPC-157 Tendon Healing Protocol: Research Dosing Comparison

Acute Injury Protocol 500mcg Once daily (AM) 2–5cm from injury site 4–6 weeks Fresh tendon tears, ruptures within 14 days of injury Highest local concentration during peak inflammation. Single dosing sufficient due to inflammatory retention Subacute/Chronic Pr

This comparison does not assign a generated winner or score.

  • Acute Injury Protocol
  • 500mcg
  • Once daily (AM)
  • 2–5cm from injury site
  • 4–6 weeks
  • Fresh tendon tears, ruptures within 14 days of injury
  • Highest local concentration during peak inflammation. Single dosing sufficient due to inflammatory retention
  • Subacute/Chronic Protocol
  • 500mcg total
  • Split: 250mcg AM, 250mcg PM
  • 8–12 weeks
  • Tendinopathy >2 weeks old, chronic overuse injuries
  • Split dosing maintains therapeutic levels across full 24-hour collagen synthesis cycle. Necessary when inflammation has resolved
  • Systemic Dosing (Not Recommended)
  • 200–300mcg
  • Once daily
  • Abdominal subcutaneous
  • Variable
  • General recovery support
  • 4× lower local tissue concentration versus site-specific injection. Inefficient for targeted tendon repair
  • High-Dose Acute Protocol
  • 750–1000mcg
  • Within 5cm of injury
  • 2–4 weeks
  • Severe acute ruptures, surgical repair augmentation
  • Used in some research models but human safety data limited above 500mcg daily. Diminishing returns above 500mcg in most contexts
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