BPC-157 Wound Healing: Comparison Across Tissue Types
Tendon-to-bone 21–28 days to functional load 14–18 days to functional load VEGF upregulation + collagen organisation University of Zagreb, 2007 Strongest evidence base. Multiple replication studies confirm 60–70% acceleration Full-thickness skin 14–16 days to
This comparison does not assign a generated winner or score.
- Tendon-to-bone
- 21–28 days to functional load
- 14–18 days to functional load
- VEGF upregulation + collagen organisation
- University of Zagreb, 2007
- Strongest evidence base. Multiple replication studies confirm 60–70% acceleration
- Full-thickness skin
- 14–16 days to complete re-epithelialisation
- 9–11 days to complete re-epithelialisation
- Fibroblast migration + angiogenesis
- University of Zagreb, 2003
- Reproducible histological improvements, but translation to human scar outcomes unclear
- Ligament (MCL)
- 28–35 days to regain 70% tensile strength
- 18–24 days to regain 70% tensile strength
- Growth factor receptor upregulation
- Croatian preclinical model, 2010
- Promising but limited replication. Single research group dominates published work
- Bone fracture
- 42–56 days to radiographic union
- 28–35 days to radiographic union
- Enhanced osteoblast activity + vascular infiltration
- University of Zagreb, 2009
- Mechanism well-characterised, but human dosing extrapolation remains speculative
- Muscle tear (gastrocnemius)
- 10–14 days to restore 80% function
- 6–9 days to restore 80% function
- Reduced fibrosis + satellite cell activation
- Rat model, 2011
- Functional recovery faster than structural. Peptide may reduce compensatory scar tissue formation