Source comparison
CJC-1295 GHRH Receptor Mechanism: Research Comparison
Native GHRH-44 100% (reference) 7 minutes 15–30 minutes No Diagnostic GH testing CJC-1295 (Mod GRF 1-29, no DAC) 95–105% 30 minutes 2–4 hours Acute pulsatile studies CJC-1295 with DAC 6–8 days 6–8 days (entire dose interval) Yes Sustained GH elevation research
This comparison does not assign a generated winner or score.
- Native GHRH-44
- 100% (reference)
- 7 minutes
- 15–30 minutes
- No
- Diagnostic GH testing
- CJC-1295 (Mod GRF 1-29, no DAC)
- 95–105%
- 30 minutes
- 2–4 hours
- Acute pulsatile studies
- CJC-1295 with DAC
- 6–8 days
- 6–8 days (entire dose interval)
- Yes
- Sustained GH elevation research
- Tesamorelin
- 90–100%
- 26–38 minutes
- 3–6 hours
- HIV lipodystrophy (FDA-approved)
- Sermorelin
- 95–100%
- 10–20 minutes
- 2–3 hours
- Anti-aging protocols (off-label)
- Bottom Line
- CJC-1295 with DAC is the only GHRH analog with week-long receptor activity from a single dose, making it uniquely suited for protocols requiring sustained GH pulse amplitude elevation without daily injections. The DAC albumin-binding mechanism extends pharmacokinetics by 200–300× compared to non-modified peptides.