Source comparison
CJC-1295 Ipamorelin Protocol Fat Loss: Comparison
Ipamorelin Solo Ghrelin receptor agonist. Triggers GH pulse (20–30 min duration) 1–2×/day 0.5–1.2kg visceral fat High Minimal Short GH pulse limits lipolytic window. Works but requires perfect timing CJC-1295 Solo (no DAC) GHRH analogue. Extends endogenous GH
This comparison does not assign a generated winner or score.
- Ipamorelin Solo
- Ghrelin receptor agonist. Triggers GH pulse (20–30 min duration)
- 1–2×/day
- 0.5–1.2kg visceral fat
- High
- Minimal
- Short GH pulse limits lipolytic window. Works but requires perfect timing
- CJC-1295 Solo (no DAC)
- GHRH analogue. Extends endogenous GH pulse duration
- 0.3–0.8kg visceral fat
- Extends pulse but lacks amplitude. Insufficient for meaningful fat oxidation
- CJC-1295 + Ipamorelin
- Synergistic: ipamorelin initiates pulse, CJC-1295 extends it (2–4 hr window)
- 1.5–2.2kg visceral fat
- Gold standard. Sustained GH elevation produces measurable fat loss without muscle catabolism
- CJC-1295 with DAC + Ipamorelin
- DAC version has 6–8 day half-life. Creates steady-state GH, not pulsatile
- Once weekly CJC + daily ipamorelin
- 0.8–1.4kg visceral fat
- Moderate
- Moderate (prolonged GH suppresses natural pulse)
- Incompatible pharmacokinetics. DAC negates the pulsatile benefit of ipamorelin
- GHRP-6 + CJC-1295
- Older ghrelin agonist. Triggers GH but also cortisol and appetite increase
- 1.2–1.8kg visceral fat
- High (cortisol spikes, prolactin elevation)
- Effective for GH release but appetite rebound and cortisol make adherence difficult