Source comparison
CJC-1295 Mechanism of Action Detailed: Comparison
CJC-1295 (with DAC) GHRH analog with albumin binding 6–8 days GHRH receptor (Gs-coupled) Amplifies existing pulses 2–6× pulse amplitude, sustained 1 week Sermorelin Unmodified GHRH analog 8–12 minutes Triggers single pulse per dose Acute pulse, requires daily
This comparison does not assign a generated winner or score.
- CJC-1295 (with DAC)
- GHRH analog with albumin binding
- 6–8 days
- GHRH receptor (Gs-coupled)
- Amplifies existing pulses
- 2–6× pulse amplitude, sustained 1 week
- Sermorelin
- Unmodified GHRH analog
- 8–12 minutes
- Triggers single pulse per dose
- Acute pulse, requires daily dosing
- Ipamorelin
- Ghrelin mimetic (secretagogue)
- 2 hours
- Ghrelin receptor (Gq-coupled)
- Triggers immediate pulse
- Rapid onset, short duration
- Exogenous GH (somatropin)
- Direct GH replacement
- 2–4 hours
- GH receptors in peripheral tissues
- Continuous elevation (suppresses endogenous pulses)
- Supraphysiological levels, negative feedback
- CJC-1295 + Ipamorelin
- Dual pathway activation
- 6–8 days + 2 hours
- GHRH + ghrelin receptors
- Synergistic pulse amplification
- 3–5× greater than either alone