Source comparison
CJC-1295 No DAC Biomarkers: Comparison
Serum IGF-1 24–72 hours post-dose Hepatic GH receptor activation, cumulative GH exposure CLIA, ELISA Indirect marker, stable, easy to collect. Does not reflect pulsatility GH Pulse Amplitude 15–120 minutes post-dose Direct pituitary GH secretion, pulse intensi
This comparison does not assign a generated winner or score.
- Serum IGF-1
- 24–72 hours post-dose
- Hepatic GH receptor activation, cumulative GH exposure
- CLIA, ELISA
- Indirect marker, stable, easy to collect. Does not reflect pulsatility
- GH Pulse Amplitude
- 15–120 minutes post-dose
- Direct pituitary GH secretion, pulse intensity
- IRMA, serial sampling
- Most direct measure of peptide efficacy. Labor-intensive
- Nitrogen Retention
- 48–72 hours cumulative
- Net anabolic protein turnover
- 24-hour urine Kjeldahl
- Functional endpoint, integrates GH + substrate availability
- Serum Amino Acid Flux
- 60–120 minutes post-dose
- Peripheral amino acid uptake, muscle protein synthesis
- LC-MS
- Acute anabolic signaling, correlates with pulse amplitude
- IGFBP-3
- IGF-1 bioavailability modulation
- CLIA
- Contextualizes IGF-1 data, influenced by nutrition