Source comparison
CJC-1295 No DAC & Ipamorelin Metabolism Research: Comparison
Peak GH Level (ng/mL) 12–20 (if timed to endogenous pulse) 15–40 (dose-dependent) 35–50 Combined protocol produces 2–3× the peak of either peptide alone. But only when both are administered within the same 30-minute window Pulse Duration (hours) 1.5–2 (extends
This comparison does not assign a generated winner or score.
- Peak GH Level (ng/mL)
- 12–20 (if timed to endogenous pulse)
- 15–40 (dose-dependent)
- 35–50
- Combined protocol produces 2–3× the peak of either peptide alone. But only when both are administered within the same 30-minute window
- Pulse Duration (hours)
- 1.5–2 (extends natural pulse)
- 1–1.5 (monophasic release)
- 2–3
- Extended duration allows sustained metabolic signaling without requiring multiple daily doses
- Cortisol Elevation
- None (GHRH pathway selective)
- None (GHS-R1a selective)
- None
- Clean GH amplification without HPA axis activation. Critical for metabolic research where cortisol confounds lipolysis data
- Metabolic Endpoint: Lipolysis
- 15–25% increase vs baseline
- 20–35% increase vs baseline
- 40–60% increase vs baseline
- The synergistic effect on fat oxidation exceeds the additive sum. Receptor cross-sensitization at the cAMP level is the likely mechanism
- Reconstitution Stability (days at 2–8°C)
- 28 days in bacteriostatic water
- 28 days (both peptides stable in same vial)
- Co-administration from a single vial is biochemically stable and simplifies dosing logistics in multi-week protocols
- Optimal Dosing Window
- 15–30 min before natural GH pulse (pre-sleep or post-exercise)
- Anytime (triggers independent pulse)
- Both peptides dosed together 30–60 min pre-sleep
- Bedtime dosing aligns with the body's largest natural GH pulse (first 90 min of deep sleep), maximizing synergistic amplification