Source comparison
CJC-1295 No DAC vs Ipamorelin vs MOD-GRF(1-29): Clearance Comparison
CJC-1295 No DAC ~30 minutes GHRH analog. Binds pituitary GHRH receptors to stimulate GH pulse 2–3× daily at 100–200 mcg Negligible plasma levels by 2–4 hours; complete renal clearance within 6 hours Best for replicating natural pulsatile GH release; requires f
This comparison does not assign a generated winner or score.
- CJC-1295 No DAC
- ~30 minutes
- GHRH analog. Binds pituitary GHRH receptors to stimulate GH pulse
- 2–3× daily at 100–200 mcg
- Negligible plasma levels by 2–4 hours; complete renal clearance within 6 hours
- Best for replicating natural pulsatile GH release; requires frequent dosing but preserves receptor sensitivity
- CJC-1295 With DAC
- 6–8 days
- GHRH analog with albumin-binding modification. Sustains GH elevation
- Once weekly at 1–2 mg
- Detectable levels persist 10–14 days; albumin-bound peptide clears slowly
- Practical for long-term protocols but creates non-physiological sustained GH elevation
- Ipamorelin
- ~2 hours
- Ghrelin mimetic. Binds ghrelin receptors (GHS-R1a) to release GH
- 2–3× daily at 200–300 mcg
- Plasma levels drop below threshold by 4–6 hours
- Often stacked with CJC-1295 no DAC; complementary pulsatile mechanisms with minimal cortisol/prolactin effects
- MOD-GRF(1-29)
- Modified GHRH. Identical to CJC-1295 no DAC
- Identical clearance to CJC-1295 no DAC
- Functionally interchangeable with CJC-1295 no DAC; naming differs by supplier but peptide sequence is the same