Source comparison
Comparison Table: Melanotan-1 Week-One Outcomes by Dose and UV Exposure
The following table compares expected outcomes at the one-week mark across three dosing protocols with and without structured UV exposure. Conservative Baseline 0.25mg SC daily None. Baseline skin tone unchanged Minimal mole darkening, no measurable change in
This comparison does not assign a generated winner or score.
- The following table compares expected outcomes at the one-week mark across three dosing protocols with and without structured UV exposure.
- Conservative Baseline
- 0.25mg SC daily
- None. Baseline skin tone unchanged
- Minimal mole darkening, no measurable change in skin reflectance
- 5–10% experience mild nausea or flushing
- Safest initiation protocol but slowest visible results. Requires 3+ weeks to see tanning even with UV
- Standard Research Protocol
- 0.5mg SC daily, no UV
- Trace darkening in pre-existing freckles only
- Moderate tyrosinase upregulation, slight reduction in sunburn threshold
- 15–25% experience transient nausea or appetite suppression
- Balanced approach. Establishes melanogenic foundation without overwhelming tolerability; visible tanning begins week 2–3
- Standard Protocol + UV
- 0.5mg SC daily + 10–15 min UVB 3x/week
- Faint overall darkening detectable under bright light
- Strong tyrosinase activity, accelerated melanin transfer to keratinocytes
- 20–30% experience side effects, mostly GI-related
- Most efficient path to visible tanning. UV exposure compounds peptide effect and advances visible pigmentation by 7–10 days
- Aggressive Initiation
- 1mg SC daily
- Minimal to faint darkening in fair-skinned subjects; slightly more in darker skin types
- High tyrosinase expression, noticeable mole/freckle intensification
- 40–60% experience moderate nausea, flushing, or fatigue in first 72 hours
- Fastest melanin synthesis but highest dropout rate due to side effects. Only suitable for subjects with prior melanotropic peptide experience