Source comparison
Comparison Table: PT-141 Biomarkers vs Standard Hormone Panels
Plasma Nitrate/Nitrite Nitric oxide pathway activation 20–40 μmol/L 60–90 μmol/L peak (90 min) Direct measure of melanocortin→NO signaling High. Correlates with arousal intensity Urinary HVA Dopamine metabolite (reward/motivation) 3–8 mg/24h 10–15 mg/24h durin
This comparison does not assign a generated winner or score.
- Plasma Nitrate/Nitrite
- Nitric oxide pathway activation
- 20–40 μmol/L
- 60–90 μmol/L peak (90 min)
- Direct measure of melanocortin→NO signaling
- High. Correlates with arousal intensity
- Urinary HVA
- Dopamine metabolite (reward/motivation)
- 3–8 mg/24h
- 10–15 mg/24h during active phase
- Tracks central dopaminergic engagement
- Moderate. Subjective desire, not erectile function
- Serum Prolactin
- Inverse dopamine tone
- 4–15 ng/mL (M), 4–25 ng/mL (F)
- 20–30% reduction at 2–4h
- Confirms dopamine pathway activation
- Moderate. Useful for protocol optimization
- DHEA-S
- Adrenal androgen (HPA modulation)
- 80–560 μg/dL (M), 35–430 μg/dL (F)
- 15–25% increase at 4–6h
- Reflects MC4R-mediated adrenal activation
- Low. Not specific to sexual function
- Total Testosterone
- Gonadal androgen synthesis
- 300–1000 ng/dL (M), 15–70 ng/dL (F)
- No significant change
- PT-141 bypasses gonadal pathway entirely
- None. Wrong mechanism
- Estradiol
- Gonadal estrogen synthesis
- 10–40 pg/mL (M), 30–400 pg/mL (F)