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Source comparison

Complete Reference Table: Every Compound in the Comparison

One row per compound, with the receptor it actually binds. Somatropin (hGH) Recombinant hormone GH receptor (JAK2/STAT5) Subcutaneous Approved, specific indications only GH deficiency, Turner syndrome, HIV wasting, short bowel Sermorelin GHRH analogue (GHRH 1-

This comparison does not assign a generated winner or score.

  • One row per compound, with the receptor it actually binds.
  • Somatropin (hGH)
  • Recombinant hormone
  • GH receptor (JAK2/STAT5)
  • Subcutaneous
  • Approved, specific indications only
  • GH deficiency, Turner syndrome, HIV wasting, short bowel
  • Sermorelin
  • GHRH analogue (GHRH 1-29)
  • GHRH receptor
  • Approval withdrawn 2009; compounded only
  • Adult GH optimization, off-label
  • Mod GRF 1-29 (CJC-1295 no DAC)
  • GHRH analogue, stabilized
  • Not approved
  • Research; short-acting GHRH pulse
  • CJC-1295 with DAC
  • GHRH analogue + albumin tether
  • Research; 5.8-8.1 day half-life
  • Tesamorelin
  • Approved (Egrifta), HIV lipodystrophy only
  • Visceral adipose reduction
  • Ipamorelin
  • Ghrelin agonist (pentapeptide)
  • GHS-R1a
  • Research; selective, no cortisol rise
  • GHRP-2
  • Ghrelin agonist
  • Research; modest prolactin/cortisol rise
  • GHRP-6
  • Research; strong hunger stimulus
  • Hexarelin
  • Research; desensitizes with repeat dosing
  • MK-677 (ibutamoren)
  • Non-peptide small molecule
  • Oral
  • Research; 24-hour IGF-1 elevation
  • HGH Fragment 176-191
  • GH C-terminal fragment
  • No GH receptor activity
  • Marketed for fat loss; releases no GH
  • HGH Fragment 176-191 sits at the bottom because it is the compound most often filed under "HGH peptides" while doing none of the things on this page. It is a fragment of the growth hormone molecule with no GH-releasing action and no GH receptor agonism, marketed on lipolysis claims. Dose it with the HGH fragment dosage calculator if you use it, and do not expect an IGF-1 response.
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