Source comparison
GHRP-2 Acetate vs GHRP-6 Acetate: Direct Comparison
GH Pulse Magnitude (100mcg dose) 2–4× baseline, peaks at 20–30 min Equivalent potency. Choice depends on secondary effects Ghrelin Receptor Affinity Moderate (selective for GHS-R1a) High (non-selective, binds GHS-R1a + CD36) GHRP-2 avoids peripheral ghrelin si
This comparison does not assign a generated winner or score.
- GH Pulse Magnitude (100mcg dose)
- 2–4× baseline, peaks at 20–30 min
- Equivalent potency. Choice depends on secondary effects
- Ghrelin Receptor Affinity
- Moderate (selective for GHS-R1a)
- High (non-selective, binds GHS-R1a + CD36)
- GHRP-2 avoids peripheral ghrelin signaling
- Appetite Stimulation
- Minimal (10–20% incidence)
- Strong (70–80% incidence within 60 min)
- GHRP-6 confounds appetite-sensitive protocols
- Cortisol Co-Secretion
- 15–25% above baseline
- 40–60% above baseline
- GHRP-2 produces less HPA axis interference
- Prolactin Elevation
- Mild, dose-dependent (>200mcg)
- Mild to moderate, dose-dependent
- Minimal clinical difference at standard doses
- Research Applications
- Metabolic studies, sleep research, appetite-neutral protocols
- Ghrelin pathway research, appetite stimulation studies
- Select based on whether ghrelin activation is target or confound