Source comparison
Half-Life Comparison: 30 Minutes vs 8 Days
The half-life gap between these two versions is not a minor difference. It is a 230-fold difference that dictates every aspect of the protocol. Plasma half-life 5.8-8.1 days Time to peak GH 2-4 hours 15-30 minutes GH elevation duration 6+ days 2-3 hours IGF-1
This comparison does not assign a generated winner or score.
- The half-life gap between these two versions is not a minor difference. It is a 230-fold difference that dictates every aspect of the protocol.
- Plasma half-life
- 5.8-8.1 days
- Time to peak GH
- 2-4 hours
- 15-30 minutes
- GH elevation duration
- 6+ days
- 2-3 hours
- IGF-1 elevation duration
- 6-14 days
- 4-8 hours
- Steady state reached
- After 2-3 weekly doses
- After each injection
- Washout period
- 2-3 weeks
- Hours
- A study in 21 healthy adults showed that weekly dosing of CJC-1295 with DAC at 30-60 mcg/kg produced dose-dependent IGF-1 increases of 1.5 to 3-fold that persisted for the full dosing interval (Teichman et al., J Clin Endocrinol Metab, 2006). The accumulation effect means that after 2-3 weeks of weekly injections, GH and IGF-1 levels remain continuously elevated rather than cycling up and down.
- With the no-DAC version, you control the timing of each GH pulse. Inject before bed: you get a GH surge during deep sleep. Inject in the morning fasted: you get a lipolytic pulse while insulin is low. Miss a dose: your levels are back to baseline within hours. This granular control is why the no-DAC version remains the preferred choice in most research protocols. Track the half-life kinetics with the Peptide Half-Life Tracker.