Source comparison
Head-to-head comparison table
Factor GHRP-6 GHRP-2 Ipamorelin GH release potency Strong Strongest Comparable to GHRP-6 Appetite stimulation Very strong Mild Minimal Cortisol increase Yes (moderate) Yes (mild) No significant increase Prolactin increase Selectivity Low Moderate Highest Cardi
This comparison does not assign a generated winner or score.
- Factor
- GHRP-6
- GHRP-2
- Ipamorelin
- GH release potency
- Strong
- Strongest
- Comparable to GHRP-6
- Appetite stimulation
- Very strong
- Mild
- Minimal
- Cortisol increase
- Yes (moderate)
- Yes (mild)
- No significant increase
- Prolactin increase
- Selectivity
- Low
- Moderate
- Highest
- Cardioprotection
- Strong (CD36)
- Limited
- Best phase
- Bulking
- Recomp
- Cutting/long-term
- Cost
- Lowest
- The honest assessment: ipamorelin is the better choice for most research protocols. It matches GHRP-6 GH output without the appetite, cortisol, and prolactin baggage. GHRP-6 earns its place in protocols where the appetite stimulation is specifically desired (bulking), where cardioprotective benefits are prioritized, or where budget is the primary constraint.
- For a broader comparison of growth hormone peptide strategies, the peptide stacking guide covers how different secretagogues combine with GHRH analogues for optimal results.