Source comparison
How to Read Melanotan-1 COA: Testing Method Comparison
HPLC Purity Percentage of target peptide vs impurities ≥95% for research-grade <90% indicates degradation or poor synthesis HPLC is the gold standard for purity quantification. Any COA without HPLC data is incomplete Mass Spectrometry Molecular weight confirma
This comparison does not assign a generated winner or score.
- HPLC Purity
- Percentage of target peptide vs impurities
- ≥95% for research-grade
- <90% indicates degradation or poor synthesis
- HPLC is the gold standard for purity quantification. Any COA without HPLC data is incomplete
- Mass Spectrometry
- Molecular weight confirmation
- Expected MW ± 1 Da
- Discrepancy >2 Da means wrong peptide or structural error
- Mass spec verifies identity. HPLC alone cannot distinguish structurally similar peptides
- LAL Endotoxin Assay
- Bacterial endotoxin concentration
- <5 EU/mg for research use
- >10 EU/mg causes pyrogenic effects in cell culture
- Endotoxin testing is often omitted by budget suppliers. Its absence is the single clearest cost-cutting signal
- Microbial Sterility
- Presence of viable bacteria or fungi
- No growth after 14 days
- Any detectable growth disqualifies the batch
- Sterility confirms no live contamination. Distinct from endotoxin testing which detects residual fragments
- Amino Acid Analysis
- Sequence confirmation
- 100% match to expected sequence
- Any substitution or deletion invalidates the peptide
- AA analysis is optional for routine batches but mandatory when HPLC or mass spec shows anomalies