Source comparison
IGF-1 LR3 Muscle Growth Protocol: Timing Comparison
Post-Training (30–60 min) Peak (2–3× baseline) Suppressed Maximal Highest anabolic signaling. Standard timing for hypertrophy protocols Optimal window for most users Fasted Morning Moderate Elevated Inhibited 40–50% reduced downstream signaling due to AMPK-mTO
This comparison does not assign a generated winner or score.
- Post-Training (30–60 min)
- Peak (2–3× baseline)
- Suppressed
- Maximal
- Highest anabolic signaling. Standard timing for hypertrophy protocols
- Optimal window for most users
- Fasted Morning
- Moderate
- Elevated
- Inhibited
- 40–50% reduced downstream signaling due to AMPK-mTOR antagonism
- Suboptimal. AMPK blocks pathway
- Pre-Bed
- Low (circadian nadir)
- Variable
- Misaligned with GH pulse timing, inconsistent results
- Avoid. Circadian mismatch
- Bilateral Split Dose
- Peak (if post-training)
- Even distribution, reduced depot formation
- Recommended for doses ≥60mcg
- Intramuscular Injection
- Localised spike
- Localised
- Creates uneven receptor saturation, premature downregulation in injected muscle
- Not recommended. Systemic distribution preferred