Source comparison
Ipamorelin Acetate vs Ipamorelin: Full Comparison
Chemical Structure Aib-His-D-2-Nal-D-Phe-Lys-NH₂ + acetate counterion Aib-His-D-2-Nal-D-Phe-Lys-NH₂ + unspecified counterion None. The peptide sequence is identical If a vendor lists 'ipamorelin' without specifying the salt form, it's almost always acetate. Re
This comparison does not assign a generated winner or score.
- Chemical Structure
- Aib-His-D-2-Nal-D-Phe-Lys-NH₂ + acetate counterion
- Aib-His-D-2-Nal-D-Phe-Lys-NH₂ + unspecified counterion
- None. The peptide sequence is identical
- If a vendor lists 'ipamorelin' without specifying the salt form, it's almost always acetate. Request a COA to confirm.
- Receptor Binding Affinity
- Kd ≈ 1.3 nM at GHS-R1a
- None. Acetate dissociates upon reconstitution
- The acetate ion doesn't interact with ghrelin receptors. Once in solution, both forms are pharmacologically identical.
- Shelf Stability (Lyophilised, −20°C)
- 18–24 months
- 18–24 months if stored as a salt form
- None. Stability depends on the salt, not the peptide
- Free-base peptides degrade within weeks. All commercial ipamorelin ships as a salt. Acetate is simply the most common.
- Reconstitution Requirement
- Bacteriostatic water, 2–8°C storage post-reconstitution
- None
- The reconstitution protocol is identical regardless of the counterion. Acetate doesn't require special handling.
- Peptide Purity (HPLC)
- ≥98% sequence purity standard
- None. Purity is a synthesis quality issue, not a salt issue
- Purity is determined during synthesis, not by the choice of counterion. Verify through third-party COA, not vendor claims.
- Total Peptide Content (mg per vial)
- 80–85% of stated mass (remainder is acetate + moisture)
- Variable depending on counterion mass
- Acetate is lighter than trifluoroacetate, so acetate salts yield slightly higher peptide content per vial
- If comparing products by cost per milligram, calculate based on total peptide content from the COA, not the label claim.