Source comparison
Ipamorelin vs Other GH Secretagogues: Research Comparison
Ipamorelin 8–13x baseline None ~2 hours Cleanest selectivity profile for GH-isolated protocols; no secondary endocrine interference GHRP-6 10–15x baseline +40–60% Variable Strong (+30–50% intake) ~2.5 hours High GH output but cortisol and appetite confounds li
This comparison does not assign a generated winner or score.
- Ipamorelin
- 8–13x baseline
- None
- ~2 hours
- Cleanest selectivity profile for GH-isolated protocols; no secondary endocrine interference
- GHRP-6
- 10–15x baseline
- +40–60%
- Variable
- Strong (+30–50% intake)
- ~2.5 hours
- High GH output but cortisol and appetite confounds limit utility in metabolic studies
- GHRP-2
- 12–18x baseline
- +25–40%
- +20–50% in females
- Moderate
- Strongest GH response but prolactin elevation confounds reproductive and metabolic endpoints
- Hexarelin
- 15–20x baseline
- +30–50%
- ~1.5 hours
- Highest GH peak but rapid desensitization (7–10 days) and cortisol surge limit chronic protocols
- CJC-1295 (DAC)
- 2–4x baseline (sustained)
- 6–8 days
- Long half-life produces tonic elevation rather than pulsatile release; different mechanism