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Long COVID Researchers Thymosin Alpha-1 Protocol: Dosing Comparison

Stanford Post-Acute COVID Clinic 1.6mg SC twice weekly 12 weeks minimum, extend to 20 weeks if biomarkers abnormal CD4+/CD8+ ratio normalization + PROMIS Fatigue score Most conservative timeline. Appropriate for newly diagnosed long COVID with mild-moderate sy

This comparison does not assign a generated winner or score.

  • Stanford Post-Acute COVID Clinic
  • 1.6mg SC twice weekly
  • 12 weeks minimum, extend to 20 weeks if biomarkers abnormal
  • CD4+/CD8+ ratio normalization + PROMIS Fatigue score
  • Most conservative timeline. Appropriate for newly diagnosed long COVID with mild-moderate symptoms
  • Yale Long COVID Multidisciplinary Care Center
  • 1.6mg SC twice weekly for 8 weeks, then once weekly for 8 weeks
  • 16 weeks total (taper phase included)
  • IL-6 reduction + 6-minute walk test improvement
  • Includes mandatory taper. Reduces risk of symptom rebound after abrupt discontinuation
  • Mount Sinai Center for Post-COVID Care
  • 8–16 weeks (biomarker-guided)
  • T-cell exhaustion marker reduction (PD-1, TIM-3 expression)
  • Research-intensive protocol requiring flow cytometry. Not accessible outside academic centers
  • European long COVID peptide protocols (aggregated literature)
  • 1.6–3.2mg SC twice weekly
  • 12–24 weeks
  • Patient-reported outcome improvement (fatigue, cognitive function)
  • Higher dose range than U.S. protocols. No evidence that >1.6mg improves outcomes
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