Source comparison
Melanotan-1 Authentication: Research-Grade vs Grey-Market Comparison
HPLC Purity ≥98% with full chromatogram Percentage claim without chromatogram, or purity 90–95% Third-party HPLC analysis Purity below 98% introduces uncontrolled variables; satellite peaks above 1% suggest synthesis contamination Mass Spectrometry 1646.88 Da
This comparison does not assign a generated winner or score.
- HPLC Purity
- ≥98% with full chromatogram
- Percentage claim without chromatogram, or purity 90–95%
- Third-party HPLC analysis
- Purity below 98% introduces uncontrolled variables; satellite peaks above 1% suggest synthesis contamination
- Mass Spectrometry
- 1646.88 Da ±1 Da with clear spectrum
- No MS data provided, or deviation >2 Da
- LC-MS or MALDI-TOF
- MS confirms peptide identity; HPLC alone cannot distinguish analogs or sequence errors
- Endotoxin Burden
- <5 EU/mg, ideally <1 EU/mg
- No LAL assay results available
- LAL (limulus amebocyte lysate) assay
- Endotoxin above 5 EU/mg confounds in vivo studies; absence of LAL data is a protocol violation
- Reconstitution Clarity
- Completely dissolves in 60 seconds, clear solution
- Cloudiness, undissolved particulates, or discoloration
- Visual inspection under controlled conditions
- Aggregation or insoluble contaminants disqualify the sample for precise dosing
- Third-Party Verification
- Independent lab CoA with batch match
- In-house testing only, or CoA batch number mismatches vial
- Cross-reference with labs like Janoshik or Colmaric
- Self-testing creates conflict of interest; third-party verification is the only unbiased standard
- Cold-Chain Compliance
- Shipped <8°C with temperature logger
- Ambient-temperature shipping or no thermal packaging
- Temperature logger data review
- Single temperature excursion above 8°C denatures peptide structure irreversibly